Born in 1957 in the city of Sofara, Mali.

He earned his BSc in 1977, and his MD in 1979 in Biochemistry from the University Paul Sabatier, Toulouse, France.

He went on to earn his PhD in Molecular and Cellular Biology in 1982 from the same university. He earned excellence awards throughout his academic studies; best student of the University of Paul Sabatier, Toulouse, 1981; and the best thesis on Leprosy, Paris, 1982.

Prof. Daffe has over 30 years of research experience that focused on the characterization of Cellular Components of the Mycobacterial Envelope. He was leading one of the well-known laboratories working on the Biochemical and Structural aspects of the Cell wall in Mycobacteria.

He was often invited to deliver talks at various seminars, scientific meetings and international conferences.

Prof. Mamadou Daffe was elected a Fellow of IAS in 2001.